OTULIN enzyme identified as "master regulator" of brain aging — disabling it made tau protein vanish from neurons while keeping cells healthy, suggesting a completely different approach to neurodegeneration than current anti-amyloid strategies.
Transcription factor rejuvenation + CRISPR editing convergence creates massive opportunity for longevity DeFi protocols and AI-driven drug discovery agents; regulatory volatility at FDA (Prasad departure, inconsistent approvals) creates arbitrage for offshore clinical trials and crypto-funded research.